Premium
Hepatitis C virus (HCV) NS5A protein: role in HCV replication and resistance to interferon‐ α
Author(s) -
Pawlotsky J.M.
Publication year - 1999
Publication title -
journal of viral hepatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 100
eISSN - 1365-2893
pISSN - 1352-0504
DOI - 10.1046/j.1365-2893.1999.00004.x
Subject(s) - ns5a , virology , hepatitis c virus , interferon , viral replication , pathogenesis , biology , virus , mechanism (biology) , hepatitis c , hepacivirus , immunology , philosophy , epistemology
The hepatitis C virus (HCV) non‐structural (NS) 5A protein appears to play an important regulatory role on viral replication and could also be involved in viral pathogenesis. HCV resistance to interferon is a complex mechanism involving multiple causes, among which certain NS5A functions could play a role.