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Mechanism of emergence of hepatitis B virus escape variants: approaches to prevention
Author(s) -
Thomas H. C.
Publication year - 1998
Publication title -
journal of viral hepatitis
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 100
eISSN - 1365-2893
pISSN - 1352-0504
DOI - 10.1046/j.1365-2893.1998.0050s2031.x
Subject(s) - epitope , virology , mechanism (biology) , hepatitis b virus , hepatitis b , virus , mutation , biology , chronic hepatitis , immune escape , antigen , immunology , medicine , genetics , gene , immune system , philosophy , epistemology
Hepatitis B virus causes a chronic infection in a large proportion of cases. One possible mechanism whereby hepatitis B avoids the host defences is by mutation of antigenic epitopes. This article reviews current views in the area.