Premium
14‐3‐3 Proteins in Pineal Photoneuroendocrine Transduction: How Many Roles?
Author(s) -
Klein D. C.,
Ganguly S.,
Coon S. L.,
Shi Q.,
Gaildrat P.,
Morin F.,
Weller J. L.,
Obsil T.,
Hickman A.,
Dyda F.
Publication year - 2003
Publication title -
journal of neuroendocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.062
H-Index - 116
eISSN - 1365-2826
pISSN - 0953-8194
DOI - 10.1046/j.1365-2826.2003.01000.x
Subject(s) - transduction (biophysics) , signal transduction , melatonin , biology , pineal gland , endocrinology , microbiology and biotechnology , medicine , function (biology) , neuroscience , biochemistry
Recent studies suggest that a common theme links the diverse elements of pineal photoneuroendocrine transduction – regulation via binding to 14‐3‐3 proteins . The elements include photoreception, neurotransmission, signal transduction and the synthesis of melatonin from tryptophan. We review general aspects of 14‐3‐3 proteins and their biological function as binding partners, and also focus on their roles in pineal photoneuroendocrine transduction.