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Progress in the development of immunotherapy for the treatment of patients with cancer[Note 1. This paper is based on a lecture delivered at ...]
Author(s) -
Rosenberg S. A.
Publication year - 2001
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1046/j.1365-2796.2001.00911.x
Subject(s) - medicine , immunotherapy , cancer , cancer immunotherapy , immunology , oncology , cancer treatment , antigen
. Rosenberg SA (National Cancer Institute, Institutes of Health, Bethesda, MD, USA). Progress in the development of immunotherapy for the treatment of patients with cancer (Review). J Intern Med 2001; 250: 462–475. Several recent developments have hallmarked progress in tumour immunology and immunotherapy. The use of interleukin‐2 (IL‐2) in cancer patients demonstrated that an immunological manipulation was capable of mediating the regression of established growing cancers in humans. The identification of the genes encoding cancer antigens and the development of means for effectively immunizing patients against these antigens has opened important new avenues of exploration for the development of effective active and cell‐transfer immunotherapies for patients with cancer.