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Toxin‐mediated haemolytic uraemic syndrome without diarrhoea
Author(s) -
Kater A. P.,
Westermann A. M.,
De Groot M. R.,
Von Dem Borne A. E. G. KR.,
Kuijper E. J.
Publication year - 2000
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1046/j.1365-2796.2000.00729.x
Subject(s) - haemolytic uraemic syndrome , medicine , haemolysis , toxin , urinary system , gastroenterology , diarrhea , gastrointestinal tract , immunology , microbiology and biotechnology , biology , escherichia coli , gene , biochemistry
. Kater AP, Westermann AM, de Groot MR, von dem Borne AEGKr (Academic Medical Centre, Amsterdam, The Netherlands). Toxin‐mediated haemolytic uraemic syndrome without diarrhoea (Case Report). J Intern Med 2000; 248: 263–265. A 52‐year‐old previously healthy man was admitted to the hospital with haematuria, painful micturition and fever. Laboratory investigation showed the presence of a haemolytic uraemic syndrome (HUS), characterized by haemolysis, renal insufficiency and mental disturbances. A urinary tract infection caused by a verotoxin‐producing E. coli other than O157:H7 was diagnosed. Treatment of this infection resulted in his complete recovery from the illness. Both the search for a focus outside the gastrointestinal tract and the search for verotoxin genes by specific polymerase chain reaction can be crucial in a patient with HUS without preceding diarrhoea.