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Nephron‐sparing surgery and renal transplantation in patients with renal cell carcinoma and von Hippel–Lindau disease
Author(s) -
David A. Goldfarb
Publication year - 1998
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1046/j.1365-2796.1998.00339.x
Subject(s) - medicine , renal cell carcinoma , transplantation , von hippel–lindau disease , nephron , disease , renal function , kidney disease , kidney , carcinoma , urology , kidney transplantation , surgery
Goldfarb DA (Cleveland Clinic Foundation, Cleveland, Ohio, USA). Nephron‐sparing surgery and renal transplantation in patients with renal cell carcinoma and von Hippel–Lindau disease (Minisymposium: MEN & VHL). J Intern Med 1998; 243 : 563–7. Renal cell carcinoma is a common manifestation of von Hippel–Lindau disease and an important cause of mortality in these patients. A contemporary approach to the treatment of localized renal cell carcinoma is outlined based upon several recently conducted multicentre reviews. When technically feasible nephron‐sparing surgery can preserve renal function without compromising long‐term survival in most patients. For those who develop end‐stage renal failure as a result of treatment for renal cell carcinoma, excellent results with a limited risk for development of recurrence can be obtained with renal transplantation.