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Sarcoidosis mimicking toxoplasmosis with severe hypercalcaemia and normal 1,25‐dihydroxy vitamin D
Author(s) -
LEVY Y.,
HAYEK T.,
FINKELSTEIN R.
Publication year - 1996
Publication title -
journal of internal medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.625
H-Index - 160
eISSN - 1365-2796
pISSN - 0954-6820
DOI - 10.1046/j.1365-2796.1996.24850000.x
Subject(s) - medicine , hypercalcaemia , sarcoidosis , toxoplasmosis , vitamin d and neurology , dermatology , pediatrics , pathology , calcium
We report a case of a female patient with sarcoidosis who presented with a generalized lymphadenopathy and a strong IgG serological test of toxoplasmosis. Progressive lymphadenopathy with a rising plasma calcium (up to 15 mg dL ‐1 ) with a normal plasma 1,25‐dihydroxy vitamin D concentration occurred later. Corticosteroid therapy resulted in prompt clinical and biochemical responses with normalization of plasma calcium and a significant reduction in 1,25‐dihydroxy vitamin D concentration. This is an exceptional presentation of sarcoidosis with severe hypercalcaemia and normal vitamin D metabolites.