Premium
Review: Rapid cycling bipolar affective disorder in people with intellectual disability: a systematic review
Author(s) -
Vanstraelen M.,
Tyrer S. P.
Publication year - 1999
Publication title -
journal of intellectual disability research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.941
H-Index - 104
eISSN - 1365-2788
pISSN - 0964-2633
DOI - 10.1046/j.1365-2788.1999.043005349.x
Subject(s) - bipolar disorder , rapid cycling , psychiatry , population , lithium (medication) , intellectual disability , psychology , cycling , systematic review , medline , medicine , clinical psychology , environmental health , archaeology , political science , law , history
Rapid cycling bipolar affective disorder has attracted renewed interest in the general adult psychiatric literature, particularly as the response to lithium prophylaxis is poor in this subgroup of patients. The present paper describes a systematic Medline/Psyclit review of case studies and small series of patients with rapid cycling bipolar affective disorder in people with intellectual disability (ID). Rapid cycling bipolar affective disorder in people with ID may differ from its occurrence in the non‐ID population in terms of a relative preponderance of males, an increased likelihood of rapid cycling onset in those with an early (prepubertal) onset of affective disorder and a different response to prophylactic drugs. The efficacy of treatment and prophylaxis of rapid cycling illnesses needs further investigation in the population with ID.