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Monoamine oxidase drugs and diet
Author(s) -
Merriman S. H.
Publication year - 1999
Publication title -
journal of human nutrition and dietetics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.951
H-Index - 70
eISSN - 1365-277X
pISSN - 0952-3871
DOI - 10.1046/j.1365-277x.1999.00143.x
Subject(s) - moclobemide , monoamine oxidase , tyramine , medicine , monoamine oxidase a , monoamine oxidase inhibitor , selegiline , drug , pharmacology , snacking , psychiatry , biochemistry , disease , obesity , anxiety , chemistry , receptor , parkinson's disease , serotonin , antidepressant , enzyme
Summary Aims: To review the literature on monoamine oxidase drugs and propose a simple diet sheet. Methods: A literature search, using a range of computer data bases and the assistance of the Mental Health Group of the British Dietetic Association. Results: MAO‐B drugs (e.g. Selegiline) do not require dietary restrictions. MAO‐A drugs and MAOI drugs do require a restriction of the intake of tyramine. The manufacturer (Roche) of Manerix (moclobemide), an MAO‐A drug, states that not more than 50 g of cheese should be eaten when taking that medication. MAOI drugs (e.g. Isocarboxazid (Cambridge), Nardil (P‐D), Parnate (SK & F)) require further dietary restrictions. Patients taking MAOI drugs should not consume more than 6 mg tyramine in a single dose (i.e. a meal or snack). Conclusion: A simple diet sheet, for use with MAOI drugs, has been devised. It lists the foods which must be avoided, those which may be taken in moderation and those which may be eaten freely.