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Serum uric acid levels in cardiovascular diseases
Author(s) -
Torun M.,
Yardım S.,
Simsek B.,
Burgaz S.
Publication year - 1998
Publication title -
journal of clinical pharmacy and therapeutics
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.622
H-Index - 73
eISSN - 1365-2710
pISSN - 0269-4727
DOI - 10.1046/j.1365-2710.1998.00125.x
Subject(s) - uric acid , medicine , pharmacology
Objective: Comparison of the serum uric acid levels of healthy people (n =71) and patients with cardiovascular diseases (CVD) ( n =62). Subjects and methods: The patients included had either experienced acute myocardial infarction (AMI) (n =31), atherosclerosis (AT) ( n =23) or ischaemia ( n=8). The mean values (x±SD) of serum uric acid levels of the control group, the patients with CVD as a whole, and patients with AMI, AT and ischaemia were 4·15±0·45 mg%, 5·6±2·06 mg%, 5·96±2·60 mg%, 5·38±1·22 mg% and 4·94±1·40 mg%, respectively. A statistically higher level of serum uric acid was found in the controls compared to the CVD patients (P < 0·05). Conclusion: The higher serum uric acid levels found in CVD patients suggests that any protective antioxidant effect which uric acid has is overwhelmed by other negative effects on pathogenesis.