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Serovars of Mycobacterium avium complex isolated from AIDS and non‐AIDS patients in Spain
Author(s) -
Torrelles J. B.,
Chatterjee D.,
Lonca J. G.,
Manterola J. M.,
Ausina V. R.,
Brennan AnD.P. J.
Publication year - 2000
Publication title -
journal of applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.889
H-Index - 156
eISSN - 1365-2672
pISSN - 1364-5072
DOI - 10.1046/j.1365-2672.2000.00958.x
Subject(s) - serotype , monoclonal antibody , mycobacterium , microbiology and biotechnology , antigen , biology , glycolipid , virology , sida , human immunodeficiency virus (hiv) , viral disease , antibody , bacteria , immunology , genetics
Antigen fingerprinting based on surface glycolipid antigens was applied to the epidemiology of clinical isolates of the Mycobacterium avium complex from 128 acquired immunodeficiency syndrome (AIDS) and 31 non‐AIDS patients from several different regions of Spain. The application of thin‐layer chromatography, gas chromatography–mass spectrometry and monoclonal antibodies, combined with ELISA, allowed a facile identification, differentiation and classification of the isolates. The cumulative results demonstrate that, among the clinical isolates, serovar 4 was predominant in both AIDS (33·6%) and non‐AIDS (22·6%) isolates. In general, the results demonstrate geographical as well as disease‐related differences in the distribution of Myco. avium complex serovars of clinical importance.