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Bactericidal activity of catechin‐copper (II) complexes against Staphylococcus aureus compared with Escherichia coli
Author(s) -
Hoshino N.,
Kimura T.,
Hayakawa F.,
Yamaji A.,
Ando T.
Publication year - 2000
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1046/j.1365-2672.2000.00800.x
Subject(s) - staphylococcus aureus , escherichia coli , copper , hydrogen peroxide , catechin , microbiology and biotechnology , chemistry , bacteria , biochemistry , biology , antioxidant , polyphenol , organic chemistry , genetics , gene
The bactericidal activity of catechin‐copper (II) complexes against Staphylococcus aureus compared with Escherichia coli was investigated in relation to the generation of hydrogen peroxide and the binding of Cu(II) ion onto the bacteria. The bactericidal activity of catechin‐Cu(II) complexes against Staph. aureus (Gram‐positive) was much lower than that against E. coli (Gram‐negative), suggesting that the binding of copper ions to the surface of bacterial cells plays an important role in the bactericidal activity of catechin‐Cu(II) complexes.