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Enhancement of growth and poly 3‐hydroxybutyrate production from Methylobacterium sp. ZP24 by formate and other organic acids
Author(s) -
Yellore V. S.,
Thakur N. B.,
Desai A. J.
Publication year - 1999
Publication title -
letters in applied microbiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.698
H-Index - 110
eISSN - 1472-765X
pISSN - 0266-8254
DOI - 10.1046/j.1365-2672.1999.00608.x
Subject(s) - formate , methylobacterium , chemistry , sucrose , yield (engineering) , bacteria , organic chemistry , food science , biochemistry , biology , materials science , catalysis , metallurgy , gene , genetics , 16s ribosomal rna
Production of the polymer, poly 3‐hydroxybutyrate (PHB), by Methylobacterium sp. ZP24 increased when sucrose‐containing medium was partially substituted with low concentrations of several organic acids. Low concentrations of formate could enhance the PHB yield 2·4‐fold and bring down the production time by 12 h. The use of formate as a growth enhancer could be successfully scaled up to the 18 litre level. The possible mechanism of enhancement is discussed.