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Newly developed resinous direct pulp capping agent containing calcium hydroxide (MTYA1‐Ca)
Author(s) -
Niinuma A.
Publication year - 1999
Publication title -
international endodontic journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.988
H-Index - 119
eISSN - 1365-2591
pISSN - 0143-2885
DOI - 10.1046/j.1365-2591.1999.00249.x
Subject(s) - pulp capping , calcium hydroxide , nuclear chemistry , chemistry , mtt assay , alkaline phosphatase , viability assay , calcium , pulp (tooth) , methacrylate , dentistry , biochemistry , polymerization , organic chemistry , cell growth , cell , medicine , enzyme , polymer
Niinuma A . Newly developed resinous direct pulp capping agent containing calcium hydroxide (MTYA1‐Ca). International Endodontic Journal , 32, 475–483 1999. Aim The aim of this study was to evaluate a newly developed resin (MTYA1‐Ca) for direct pulp capping. Methodology The powder of MTY1‐Ca is composed of 89.0% microfiller, 10.0% calcium hydroxide and 1.0% benzoyl peroxide and was mixed with liquid (67.5% triethyleneglycol dimethacrylate, 30.0% glyceryl methacrylate, 1.0% o‐methacryloyl tyrosine amide, 1.0% dimethylaminoethylmethacrylate, and 0.5% camphorquinone). The shear bond, diametral tensile, bending and compressive strengths were measured. The alkaline activity of the eluate dissolved from MTYAl‐Ca was calculated. Cell viability by MTT assay and alkaline phosphatase (ALPase) activity were evaluated from dental pulp fibroblast reaction to the eluate dissolved from MTYAl‐Ca. Histopathological studies of the response to exposed dental pulp of beagle dogs were completed with Dycal as a control. Results The physical properties of MTYAl‐Ca were significantly superior to those of Dycal. It was impossible to measure these properties with Dycal because of poor physical properties. Both MTYA1‐Ca and Dycal maintained high levels of alkaline activity (pH 10.96–12.20) over the 168‐h duration of the study. Cell viability by MTT assay in the intact eluate of MTYAl‐Ca was significantly higher than that of Dycal, whilst ALPase showed no difference between MTYAl‐Ca and Dycal. A dentine bridge formed more slowly under MTYA1‐Ca than under Dycal, but similar amounts had formed at 90 days. Conclusions MTYAl‐Ca has the potential to be used as a direct pulp capping material.