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The D7 family of salivary proteins in blood sucking diptera
Author(s) -
Valenzuela J. G.,
Charlab R.,
Gonzalez E. C.,
De MirandaSantos I. K. F.,
Marinotti O.,
Francischetti I. M. B.,
Ribeiro J. M. C.
Publication year - 2002
Publication title -
insect molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.955
H-Index - 93
eISSN - 1365-2583
pISSN - 0962-1075
DOI - 10.1046/j.1365-2583.2002.00319.x
Subject(s) - biology , subfamily , culex quinquefasciatus , aedes aegypti , anopheles stephensi , anopheles gambiae , salivary gland , culex , blood sucking , phlebotomus , zoology , aedes , superfamily , midgut , evolutionary biology , genetics , ecology , immunology , larva , gene , malaria , parasite hosting , leishmania , biochemistry , world wide web , computer science
The D7 subfamily of salivary proteins is widespread in blood sucking Diptera and belongs to the superfamily of pheromone/odourant binding proteins. Although D7 proteins are among the most abundant salivary proteins in adult female mosquitoes and sand flies, their role in blood feeding remains elusive. In the present work we report the sequence of seventeen novel D7 proteins, and propose an evolutionary scenario for the appearance of the several forms of this protein, based on a total of twenty‐one sequences from Culex quinquefasciatus , Aedes aegypti, Anopheles gambiae, An. arabiensis, An. stephensi, An. darlingi mosquitoes and Lutzomyia longipalpis and Phlebotomus papatasi sand flies.