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Ikirara , a novel transposon family from the malaria vector mosquito, Anopheles gambiae
Author(s) -
Romans P.,
Bhattacharyya R. K.,
Colavita A.
Publication year - 1998
Publication title -
insect molecular biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.955
H-Index - 93
eISSN - 1365-2583
pISSN - 0962-1075
DOI - 10.1046/j.1365-2583.1998.71046.x
Subject(s) - anopheles gambiae , biology , transposable element , inverted repeat , genetics , genome , anopheles stephensi , locus (genetics) , gene duplication , vector (molecular biology) , gene , malaria , aedes aegypti , botany , larva , immunology , recombinant dna
Members of a novel transposon family, Ikirara , were found in the genome of the malaria vector Anopheles gambiae . They are most abundant in A. gambiae sensu stricto , but related sequences were found in all four other tested members of this species complex. No relatives were found in A. funestus or A. stephensi . Ikirara1 , the first isolated family member, was found between two of the tandem Vitellogenin (Vg) genes. Because it was found at this location in G3 and only one of nine other A. gambiae s.s. strains examined, and because its 216 bp inverted terminal repeats are 100% identical, transposition to this locus may have been recent. Ikirara1 inverted repeat terminal sequences are similar to those of DNA to DNA transposons of the mariner/Tc1 and hAT superfamilies. Also similar to mariner/Tc1 elements, insertion of Ikirara1 apparently created a duplication of the dinucleotide TA at the target site.