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Glioblastoma multiforme in a mature ovarian teratoma with recurring brain tumours
Author(s) -
Yadav A,
LellouchTubiana A,
Fournet J C,
Quazza J E,
Kalifa C,
SainteRose C,
Jaubert F
Publication year - 1999
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1046/j.1365-2559.1999.00695.x
Subject(s) - glioblastoma , pathology , teratoma , ovarian teratoma , context (archaeology) , medicine , ovary , primitive neuroectodermal tumor , biology , sarcoma , cancer research , paleontology
Aims We report a case study to highlight the occurrence of glioblastoma multiforme in an ovarian teratoma. Methods and results A 10‐year‐old girl presented with a left frontal lobe primitive neuroectodermal tumour which was successfully treated. After 6 uneventful years, she developed glioblastoma multiforme located posterior to the site of the initial tumour. Six years later, she presented with a mature cystic teratoma containing glioblastoma multiforme. Conclusions Glioblastoma in an ovarian teratoma is an exceptional event, which might have an initial clinical presentation as a metastatic brain tumour. Alternatively, recurring glial tumours may occur in a genetically predisposed person; the role of radiation and chemotherapy in this context remains to be elucidated.