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Focal malakoplakia in chronic periapical periodontitis
Author(s) -
Carlo Pesce,
G Pate,
Stephanie A. Valente,
R Tanzi
Publication year - 1999
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1046/j.1365-2559.1999.00574.x
Subject(s) - malakoplakia , malacoplakia , homogeneous , periodontitis , pathology , lesion , macrophage , periapical periodontitis , medicine , dentistry , chemistry , biochemistry , physics , in vitro , thermodynamics
Aims Three cases of chronic periapical periodontitis including focal areas with malakoplakia changes are reported. Methods and results These areas included both von Hansemann‐type macrophages and periodic acid–Schiff‐positive, iron‐ and calcium‐containing concretions. Some concretions corresponded to spherules with a targetoid configuration, thus fitting the morphological criteria for classical Michaelis–Gutmann bodies. Conclusion The vast majority of the cases of malakoplakia that have been reported in the literature corresponded to a characteristic, fairly homogeneous lesion, but a few instances of focal malakoplakia have been described in various chronic conditions. These considerations support the opinion that the local conditions for the production of Michaelis–Gutmann bodies may occur focally in diseases characterized by macrophage accumulation.