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Familial mediterranean fever and acute myocardial infarction secondary to coronary vasculitis
Author(s) -
Serrano R,
Martínez M A,
Andrés A,
Morales J M,
Samartin R
Publication year - 1998
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1046/j.1365-2559.1998.00462.x
Subject(s) - medicine , myocardial infarction , vasculitis , cardiology , familial mediterranean fever , disease
Aims We report a case study to elucidate the pathogenesis of polyarteritis nodosa (PAN) type vasculitis, a rare complication of familial mediterranean fever (FMF). Methods and results A woman with amyloidosis complicating FMF underwent a cadaveric renal transplantation and 5 years later suffered an acute myocardial infarction secondary to an isolated coronary vasculitis. Conclusions The histopathological findings of the vasculitis were not in keeping with PAN. We postulated that the pathogenesis of vasculitis in FMF is different from that of the classic PAN and might be similar to the mechanism of the serosal inflammation.