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Human immunodeficiency virus type 1 in an unusual cystic lymphoepithelial lesion of the lung
Author(s) -
MARIE B.,
LABOUYRIE E.,
SCHEID P.,
SIAT J.,
MÉNARD O.,
COSMIDIS I.,
PLÉNAT F.,
VIGNAUD J.M.
Publication year - 1997
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1046/j.1365-2559.1997.5820823.x
Subject(s) - lung , lesion , medicine , pathology , human immunodeficiency virus (hiv) , virus , virology
Aims : We present the clinical and histopathological findings of an unusual pulmonary cystic lymphoepithelial lesion in an HIV sero‐positive patient. Methods and results : The 32‐year‐old female patient developed two nodules in the vicinity of the right and left hila. Left upper lobectomy showed a 40‐mm wide cystic lesion. The cyst wall was lined by a squamous epithelium and lymphoid tissue with a marked follicular hyperplasia and a prominent follicular cell dendritic network expressing HIV major core protein p24. Conclusions : The absence of an Epstein–Barr virus infected lymphoid population and monoclonal immunoglobulin gene rearrangement supported the benign nature of the lesion.