Premium
Cystadenoma of spermatic cord resembling ovarian serous epithelial tumour of low malignant potential: immunohistochemical study suggesting Müllerian differentiation
Author(s) -
MCCLUGGAGE W.G.,
SHAH V.,
NOTT C.,
CLEMENTS B.,
WILSON B.,
HILL C.M.
Publication year - 1996
Publication title -
histopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.626
H-Index - 124
eISSN - 1365-2559
pISSN - 0309-0167
DOI - 10.1046/j.1365-2559.1996.272317.x
Subject(s) - pathology , immunohistochemistry , serous fluid , malignancy , biology , serous cystadenoma , cyst , staining , ovary , cystadenoma , medicine , endocrinology , pancreas
A cystic lesion of the spermatic cord resembling an ovarian serous epithelial tumour of low malignant potential or borderline malignancy is reported. Immunohistochemical staining and electronmicroscropic examination suggested epithelial rather than mesothelial differentiation of the cyst lining cells. There was strong positive immunohistochemical staining of cyst lining cells for CA 125, providing evidence for Müllerian differentiation. A flow cytometric analysis of nuclear DNA content revealed a diploid profile.