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Value of magnetic resonance imaging for the diagnosis and follow‐up of haemophilic arthropathy
Author(s) -
Dobón M.,
Lucía J. F.,
Aguilar C.,
Mayayo E.,
Roca M.,
Solano V.,
Peña A.,
Giralt M.,
Ferrández A.
Publication year - 2003
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1046/j.1365-2516.2003.00702.x
Subject(s) - medicine , magnetic resonance imaging , hemarthrosis , elbow , joint effusion , radiology , arthropathy , physical examination , synovitis , cartilage , nuclear medicine , kappa , osteoarthritis , arthritis , pathology , anatomy , alternative medicine , linguistics , philosophy
Summary. An orthopaedic assessment of the joint status of seven severe haemophiliacs (mean age 12.5 y – range 8.9–15.5) on prophylactic treatment (PT) by magnetic resonance imaging (MRI) and physical examination was carried out. Median duration of PT of these patients was 84 months (range 32–107). A locally designed MRI joint score considering seven parameters (1 – joint effusion,2 – synovial membrane thickening, 3 – haemosiderin deposits, 4 – joint cartilage injury, 5 – subchondral bone erosion, 6 – subchondral bone cysts,7 – osteonecrosis) was used (maximum score = 13 points). MRI scans were performed in 17 joints (nine ankles, seven knees and one elbow): mean MRI scores for the affected joints was 5.1. A poor consistency between physical examination and MRI findings or the real extent of joint damage was found (Cohen kappa index 0.320). MRI is a precise non‐invasive tool for the assessment of early joint cartilage and synovium pathological changes still undetectable by physical examination or conventional X‐rays in the haemophilic setting.