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Conduct of clinical trials in developing countries
Author(s) -
KASPER C. K.
Publication year - 2002
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1046/j.1365-2516.2002.00594.x
Subject(s) - medicine , informed consent , clinical trial , developing country , balance (ability) , research ethics , nursing , family medicine , alternative medicine , economic growth , psychiatry , physical therapy , pathology , economics
Research subjects in developing countries may be especially vulnerable to exploitation. Scrupulous care should be taken to maintain the basic principles of ethical trial conduct: the right of participants to make their own informed decisions, a favorable balance of benefit to risk, good trial design, candour about results, and, above all, use of honourable investigators. Involvement of local participants in planning a trial helps ensure both culturally‐sensitive protocols and consents and also maximum benefit to patients and to local research infrastructure.