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Successful outcome of a cirrhotic patient with postoperative haematuria treated with a single high dose of recombinant factor VIIa
Author(s) -
Lucía J. F.,
Aguilar C.,
Orna E.,
Allepuz C.,
Giralt M.,
Carrasco V.,
Simón M. A.
Publication year - 2001
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1046/j.1365-2516.2001.00568.x
Subject(s) - medicine , recombinant factor viia , refractory (planetary science) , factor viia , surgery , coagulation , tissue factor , physics , astrobiology
Recombinant factor VIIa (rfVIIa) has been widely used for the treatment and prevention of bleeding episodes in haemophiliacs with high‐titre inhibitors. High single doses are the treatment of choice for joint and muscle bleeds in those patients. There are only a few reports on the value of rfVIIa in cirrhotic patients with haemostatic impairment but this drug can consistently correct the prothrombin time in these individuals. We report a case of a good response to a single high dose of rfVIIa in a patient with advanced liver disease who suffered from severe refractory postoperative haematuria.