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Management of a premature infant with moderate haemophilia A using recombinant factor VIII
Author(s) -
R F Gale,
Michael F. Hird,
B. T. Colvin
Publication year - 1998
Publication title -
haemophilia
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.213
H-Index - 92
eISSN - 1365-2516
pISSN - 1351-8216
DOI - 10.1046/j.1365-2516.1998.00201.x
Subject(s) - medicine , haemophilia , pediatrics , haemophilia a , recombinant dna , genetics , biology , gene
The birth of a very premature infant with haemophilia A is a rare event. In this case report the problems posed in the management of a child with a factor VIII level of 0.03 IU mL −1 born at 28 weeks of gestation and weighing 1590 g are considered. The value of recombinant factor VIII, the pharmacokinetics of factor VIII in this situation and the importance of close cooperation between paediatricians and haematologists are discussed.