Haemophilia A: two cases showing unusual features at birth

We report two patients with severe Haemophilia A, factor VIII < 2 u dL −1 , diagnosed at birth, through isolated bleeding in the adrenal gland (case 1) and through a haeatoma in the liver (case 2). In these two clinical cases, the vital emergency, with haeorrhagic shock, required early diagnosis of the hereditary coagulation defect. Generally at birth, any unexplained bleeding should prompt screening for Haemophilia. In the newborn period, the PTT is inadequate for many reasons and the laboratory evaluation must include factor VIII and IX levels.