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A decade of site‐ and phosphorylation state‐specific antibodies : recent advances in studies of spatiotemporal protein phosphorylation
Author(s) -
Nagata Kohichi,
Izawa Ichiro,
Inagaki Masaki
Publication year - 2001
Publication title -
genes to cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.912
H-Index - 115
eISSN - 1365-2443
pISSN - 1356-9597
DOI - 10.1046/j.1365-2443.2001.00454.x
Subject(s) - biology , phosphorylation , protein phosphorylation , antibody , signal transduction , computational biology , cytoskeleton , microbiology and biotechnology , immunology , protein kinase a , genetics , cell
From 1990 to 2001, numerous site‐ and phosphorylation state‐specific antibodies have been developed and many are now commercially available. These antibodies have facilitated understanding of the cytoskeletal organization, signal transduction and transcriptional mechanisms as well as clinical diseases. This review is an attempt to cover all these aspects.