Premium
Introns and gene evolution
Author(s) -
De Souza Sandro J.,
Long Manyuan,
Gilbert Walter
Publication year - 1996
Publication title -
genes to cells
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.912
H-Index - 115
eISSN - 1365-2443
pISSN - 1356-9597
DOI - 10.1046/j.1365-2443.1996.d01-264.x
Subject(s) - biology , intron , exon , gene , exon shuffling , genetics , shuffling , computational biology , molecular evolution , evolutionary biology , alternative splicing , phylogenetic tree , computer science , programming language
In one scenario of gene evolution, exon shuffling has a fundamental role in increasing gene diversity. As DNA sequences accumulate in the databases, the picture of the intron/exon structures of genes becomes more and more clear. We discuss in this review some features of this picture that suggest that introns have been present since the early stages of evolution, and that exon shuffling was a fundamental process in the construction of ancient as well as modern genes.