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Moderate exercise, postprandial lipaemia and triacylglycerol clearance
Author(s) -
Gill J. M. R.,
Mees G. P.,
Frayn K. N.,
Hardman A. E.
Publication year - 2001
Publication title -
european journal of clinical investigation
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.164
H-Index - 107
eISSN - 1365-2362
pISSN - 0014-2972
DOI - 10.1046/j.1365-2362.2001.00799.x
Subject(s) - postprandial , medicine , meal , endocrinology , bolus (digestion) , physical exercise , area under the curve , insulin
Moderate intensity exercise reduces postprandial triacylglycerol (TG) concentrations. We tested whether this reflects increased TG clearance. Eight normotriglyceridaemic men, aged 48·3 ± 7·3 years (mean ± SD), performed two oral fat tolerance tests (blood samples taken in the fasted state and for six hours after a high‐fat meal containing 1·00 g fat, 0·97 g carbohydrate, 58 kJ energy kg −1 fat‐free body mass) and two intravenous fat tolerance tests (blood samples in the fasted state and after a bolus injection of Intralipid, 0·1 g fat kg −1 body mass). The afternoon before one oral and one intravenous test, subjects walked briskly for 90 min; no exercise was performed before the control tests. Prior exercise reduced fasting TG concentration similarly in the oral (16 ± 7 %) (mean ± SEM) and intravenous (18 ± 7 %) tests, and reduced postprandial TG concentrations in the oral test by 18 ± 6 % (all P < 0·05). However, prior exercise did not increase Intralipid clearance (disappearance curve slopes: control, 4·69 ± 0·49 % min −1 ; exercise, 4·85 ± 0·40 % min −1 ). These data suggest that mechanisms other than increased TG clearance mediate the lower postprandial TG concentrations seen after moderate exercise.