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Cytology suggestive of glandular neoplasia: outcomes and suggested management
Author(s) -
Hare A. A.,
Duncan A. R.,
Sharp A. J.
Publication year - 2003
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1046/j.1365-2303.2003.01020.x
Subject(s) - medicine , malignancy , cervix , cytology , adenocarcinoma , squamous intraepithelial lesion , cervical intraepithelial neoplasia , carcinoma in situ , pathology , uterine cervix , squamous carcinoma , intraepithelial neoplasia , carcinoma , gynecology , cervical cancer , cancer , prostate
Eighty‐three cases having a cervical smear result showing abnormal glandular cells were identified and matched up with the diagnostic histology result. Thirty‐four (41.0%) were associated with malignancy and 26 (31.3%) with a cervical intraepithelial lesion without invasion. Thirty‐eight (45.8%) had conditions of the cervix as follows: 12 cases had invasive disease of the cervix; nine (10.8%) adenocarcinoma of cervix and three (3.6%) squamous carcinoma of cervix. Nineteen (22.9%) had cervical intraepithelial neoplasia (CIN/SIL) alone and seven (8.4%) had cervical glandular intraepithelial neoplasia (CGIN) ± CIN. There were 16 (19.3%) cases with malignancies of the uterine corpus and six (7.2%) had a malignancy arising from another primary site. Twenty‐three (27.7%) had no malignant or pre‐malignant condition. The risk of malignancy was related to age and ranged from 18.2% in those under 35 years to 67.9% in those 55 years and over. A protocol for the management of these cases is described.