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Evaluation of thin‐layer methods in urine cytology
Author(s) -
Wright R. G.,
Halford J. A.
Publication year - 2001
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1046/j.1365-2303.2001.00341.x
Subject(s) - urine cytology , medicine , urine , thin layer , cytology , liquid based cytology , urinary system , urology , pathology , layer (electronics) , cancer , materials science , cystoscopy , cervical cancer , composite material
Evaluation of thin‐layer methods in urine cytology Conventional cytospin smears prepared from urinary tract specimens were compared with two new thin layer techniques, i.e. ThinPrep ® and AutoCyte PREP™. Cellularity, cell preservation, background features, detection rate, screening time and ease of preparation were evaluated. Thin‐layer techniques when applied to urine cytology were found to improve cell yield and cell preservation, and reduce background artefact. The reporting rate for abnormal urothelial cells was comparable to conventional cytospin smears, as was screening time. Laboratory staff found the methodologies to be practicable and easily incorporated into a large routine diagnostic service. We conclude that a one‐slide thin‐layer urine preparation is comparable to four cytospin slides in the detection of urothelial abnormalities, and that both ThinPrep ® and AutoCyte PREP™ have comparable features.