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Potentially difficult smears of women with squamous cell carcinoma pose fewer problems when PAPNET is used for primary screening
Author(s) -
Kok M. R.,
SchreinerKok P. G.,
Veen G.,
Boon M. E.
Publication year - 1999
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1046/j.1365-2303.1999.00194.x
Subject(s) - medicine , pathology , basal cell , cytopathology , gynecology , cytology
Potentially difficult smears of women with squamous cell carcinoma pose fewer problems when PAPNET is used for primary screening The diagnosis of squamous cell carcinoma (SCC) on a cervical smear is often far from easy. This study reports the analysis of 40 true‐positive SCC smears detected in primary PAPNET screening and eight false‐negative (FN) conventionally screened smears. All FN cases contained sparse abnormal material (< 10% of the slide). In these potentially difficult cases the diagnosis on the PAPNET images was not hard. Statistical analysis of the quantitative data indicated that the PAPNET images of the FN cases and the true‐positive cases differed in some aspects. PAPNET highlighted the importance of background information (old blood, fibrin and necrosis). In addition, all FN smears contained cancer cells in the PAPNET images, allowing a correct diagnosis.