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Metaplastic carcinomas of the breast—fine needle aspiration (FNA) cytology findings
Author(s) -
NOGUEIRA M.,
MENDONÇA S. ANDRÉ AND E.
Publication year - 1998
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1046/j.1365-2303.1998.00118.x
Subject(s) - metaplastic carcinoma , cytopathology , medicine , pathology , fine needle aspiration , cytology , carcinoma , giant cell , pleomorphic adenoma , biopsy , breast cancer , cancer , salivary gland
nogueira m., andré s. and mendonça e. . (1998) Cytopathology 9, 291–300 Metaplastic carcinomas of the breast—fine needle aspiration (FNA) cytology findings Metaplastic carcinomas of the breast are defined by mesenchymal and/or squamous cell components associated with ductal carcinoma and may raise diagnostic problems in FNA cytology. We reviewed FNA smears of a series of nine cases; seven were compared with histological sections and two with cell‐block sections. The cytological pattern was diagnostic of carcinoma in six cases; in two cases a diagnosis of sarcoma/phyllodes tumour was considered, as cells were predominantly spindle‐shaped. One case had a pleomorphic adenoma type pattern. The cytological findings suggesting a diagnosis of metaplastic carcinoma include a liquid aspirate, a proteinaceous or chondromyxoid background and a poorly differentiated tumour with multinucleated giant cells, neoplastic or histiocytic. A definite diagnosis requires the presence of both carcinomatous and metaplastic (squamous/mesenchymal) components.