Premium
Posters. P14 Adenocarcinoma of cervix a cyto‐histopathological correlation
Author(s) -
Gupta Limci,
Dina Roberto
Publication year - 2003
Publication title -
cytopathology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.512
H-Index - 48
eISSN - 1365-2303
pISSN - 0956-5507
DOI - 10.1046/j.1365-2303.14.s1.1_30.x
Subject(s) - medicine , cervix , adenocarcinoma , histopathology , cytology , biopsy , incidence (geometry) , retrospective cohort study , sampling (signal processing) , gynecology , pathology , radiology , cancer , filter (signal processing) , computer science , computer vision , physics , optics
Aim The current study was undertaken to determine the sensitivity of cytology smears in the detection of cervical adenocarcinoma, to study the incidence of CIN lesions with adenocarcinoma and to estimate sampling, screening and diagnostic errors in this cohort of cytological smears. Methods Retrospective analysis of all cases of adenocarcinoma of cervix diagnosed in the histopathology department at Hammersmith hospital over the past 10 years (January 1993 till December 2002) either by biopsy or resection specimen. Initially 69 cases of adenocarcinoma of cervix were identified of which nine had several biopsies from the same patients and seven represented either local spread or metastasis. Thus 16 cases were excluded and thereby 53 cases met the criteria for inclusion. Results Fifty‐three adenocarcinomas were identified, either pure or combined with squamous lesions. The results showed the association of adenocarcinoma with CIN lesions to be 27.3% (one CIN1, three CIN2, 11 CIN3). Cervical smears were available for review in 25 cases. 1 Analysis of cervical smearsTotal Negative Positive Not done Records not found53 07 18 18 10The sensitivity of cytology smears was 68% for all HGEA (High Grade Epithelial Abnormalities); 56% for all glandular lesions and 40% for pure adenocarcinomas. Upon review sampling error was calculated to be 4%; interpretation error was 4% and diagnostic error upon review 0%. Conclusion The current study provides an encouraging data regarding the sensitivity of Pap smears in detecting adenocarcinoma of cervix and shows a good cytopathological correlation.