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Anaplastic pseudothyroiditis
Author(s) -
Basaria Shehzad,
Udelsman Robert,
TejedorSojo Javier,
Westra William H.,
Krasner Alan S.
Publication year - 2002
Publication title -
clinical endocrinology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.055
H-Index - 147
eISSN - 1365-2265
pISSN - 0300-0664
DOI - 10.1046/j.1365-2265.2002.01495.x
Subject(s) - medicine , histopathology , thyroid , anaplastic carcinoma , anaplastic thyroid cancer , endocrinology , thyroid carcinoma , pathology , thyroid cancer
Summary Anaplastic thyroid carcinoma (ATC) is one of the most aggressive solid tumours. It generally presents as a rapidly enlarging thyroid mass and produces local symptoms associated with mass effect. One of the very rare presentations of ATC is thyrotoxicosis. We report a patient with ATC whose course was complicated by severe thyrotoxicosis. His symptoms were controlled with beta‐blockers. Two weeks into hospitalization, the patient became hypothyroid. Histopathology showed destruction of the normal thyroid follicles by the invasion of the tumour. As this form of thyrotoxicosis resembles various thyroiditides, we hereby refer this condition as ‘anaplastic pseudothyroiditis’.