Open Access90K (Mac‐2 BP) in human milk
Author(s) -
D'OSTILIO N.,
SABATINO G.,
NATOLI C.,
ULLRICH A.,
IACOBELLI S.
Publication year - 1996
Publication title -
clinical & experimental immunology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.329
H-Index - 135
eISSN - 1365-2249
pISSN - 0009-9104
DOI - 10.1046/j.1365-2249.1996.40745.x
Subject(s) - glycoprotein , lectin , immunology , breast milk , lactation , pregnancy , biology , human breast milk , galectin , medicine , endocrinology , microbiology and biotechnology , biochemistry , genetics
Human 90K, also known as Mac‐2 binding protein (Mac‐2 BP), is a secreted glycoprotein which is widely expressed, binds to the human macrophage‐associated lectin Mac‐2, and may have a role in host defence. We have measured the concentrations of 90K in human breast milk from eight healthy mothers delivering mature healthy infants after full‐term pregnancy using a specific immunoenzymatic assay. Maximal 90K concentrations were observed on days 2–3 post‐partum, and ranged from 13.4 to 79.2 μg/ml. The concentrations of 90K in the milk had no correlation with those in the maternal blood.