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Haemorrhagic bullae in a case of paroxysmal nocturnal haemoglobinuria
Author(s) -
White J. M. L.,
Watson K.,
Arya R.,
Du Vivier A. W. P.
Publication year - 2003
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.2003.01363.x
Subject(s) - medicine , haemolysis , fibrin , thrombosis , biopsy , trunk , skin biopsy , dermatology , surgery , pathology , immunology , ecology , biology
Summary Paroxysmal nocturnal haemoglobinuria is a clonal stem cell disorder manifesting as haemolysis, bone marrow failure and thrombosis. We report a rare cutaneous manifestation on the trunk of a 40‐year‐old patient. Skin biopsy revealed the presence of fibrin thrombi in the capillaries. The eruption responded within days after commencing oral corticosteroids.