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Persistent anticonvulsant hypersensitivity syndrome responding to ciclosporin
Author(s) -
Harman K. E.,
Morris S. D.,
Higgins E. M.
Publication year - 2003
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.2003.01267.x
Subject(s) - ciclosporin , medicine , anticonvulsant , drug , hypersensitivity reaction , dermatology , pharmacology , chemotherapy , immunology , epilepsy , surgery , psychiatry
Summary The drug hypersensitivity syndrome is a severe, multisystem reaction that typically develops within 2 months of starting a drug. We describe a case which has been unusually persistent, requiring prolonged treatment with systemic corticosteroids and after 1 year, ciclosporin. To the best of our knowledge, the use of ciclosporin for the treatment of the drug hypersensitivity syndrome has not been described previously.