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Cutaneous dissemination of nasal NK/T‐cell lymphoma with bone marrow, liver and lung involvement
Author(s) -
Chang S. E.,
Lee S. Y.,
Choi J. H.,
Sung K. J.,
Moon K. C.,
Koh J. K.
Publication year - 2002
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.2002.00991.x
Subject(s) - medicine , lymphoma , bone marrow , lung , pathology , radiation therapy , metastasis , chemotherapy , nose , cancer , surgery
Summary We describe a 32‐year‐old Korean man with a primary nasal natural killer (NK)/T‐cell lymphoma (NKTCL). Combination chemotherapy and radiotherapy resulted in initial complete remission. However, cutaneous dissemination to the trunk and proximal extremities occurred 16 months later and further investigations revealed involvement of the liver, lymph nodes, lung and bone marrow. Nasal CD56+ NKTCL is mostly localized to the nasal area but also shows a predilection for other sites, such as skin. Cutaneous dissemination may be an indicator of widespread metastasis to internal organs and is consistently fatal.