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Treatment of acrodermatitis continua of Hallopeau with oral propylthiouracil and methotrexate
Author(s) -
Chowdhury M. M. U.,
Motley R. J.
Publication year - 2001
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.2001.00911.x
Subject(s) - propylthiouracil , medicine , pancytopenia , acrodermatitis , methotrexate , dermatology , pediatrics , surgery , pathology , bone marrow , alternative medicine , thyroid
A 71‐year‐old man with acrodermatitis continua of Hallopeau was treated successfully with a combination of oral propylthiouracil and methotrexate. After 14 weeks, he developed acute pancytopenia, an uncommon idiosyncratic side‐effect of propylthiouracil, and presented with a life‐threatening methicillin‐resistant Staphylococcus aureus pneumonia. This illustrates the potential value and associated risks of propylthiouracil in the management of this difficult condition.