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Epstein–Barr virus‐associated peripheral T‐cell lymphoma in adults with hydroa vacciniforme‐like lesions
Author(s) -
Cho KwangHyun,
Kim ChulWoo,
Heo DaeSeog,
Lee DongSoon,
Choi WonWoo,
Rim JongHyun,
Han WonSuk
Publication year - 2001
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.2001.00805.x
Subject(s) - dermis , pathology , medicine , lymphoma , virus , biopsy , epstein–barr virus , atypical lymphocyte , vasculitis , skin biopsy , lymphocytosis , subcutaneous tissue , immunology , disease
We describe two Korean adult patients who had necrotizing papulovesicles mainly on their faces. Skin biopsy specimens showed perivascular and periadnexal infiltrate of atypical lymphoid cells with vasculitis in the dermis and subcutaneous tissue. In situ hybridization demonstrated a latent infection of Epstein–Barr virus in the majoriy of lymphoid cells in the dermis. These patients were diagnosed as having T‐cell lymphoma. Interestingly, large granular lymphocytosis was found in the peripheral blood of Case 2.