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Tissue‐engineered dermal skin grafting in the treatment of ulcerated necrobiosis lipoidica
Author(s) -
Owen C. M.,
Murphy H.,
Yates V. M.
Publication year - 2001
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.2001.00789.x
Subject(s) - necrobiosis lipoidica , medicine , microangiopathy , skin grafting , dermatology , diabetes mellitus , surgery , endocrinology
Necrobiosis lipoidica is a well recognized but comparatively rare cutaneous complication of diabetes mellitus. The aetiology is probably multifactorial with microangiopathy, immune complex formation, abnormal collagen synthesis and breakdown, and altered haemostasis all thought to play a part. Necrobiosis lipoidica often proves very resistant to treatment. We report a case of a 44‐year‐old woman with ulcerated necrobiosis lipoidica that healed following grafting with a tissue‐engineered living dermal tissue.