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Treatment of pruritus by capsaicin in a patient with pityriasis rubra pilaris receiving RE‐PUVA therapy
Author(s) -
Neess C. M.,
Hinrichs R.,
Dissemond J.,
Herrmann G.,
Poswig A.,
Serverallanras M.,
Hunzelmann N.,
Brenneisen P.,
Meewes C.,
Krieg T.,
ScharffetterKochanek K.
Publication year - 2000
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.2000.00616.x
Subject(s) - pityriasis rubra pilaris , puva therapy , medicine , capsaicin , dermatology , psoriasis , receptor
Pityriasis rubra pilaris (PRP) is characterized by redness of the skin, scaling and a variable degree of pruritus. We present a patient with extremely itchy PRP successfully treated with oral retinoids and photochemotherapy with 8‐methoxypsoralene (RE‐PUVA) and topical capsaicin. The PRP‐related pruritus which clearly preceded photochemotherapy and for which no other cause was apparent was relieved with capsaicin. This single case report provides evidence that topical capsaicin may be a useful therapeutic option in treating PRP‐associated pruritus where antihistamines have been unsuccessful.