Premium
Graves' disease presenting as localized myxoedematous infiltration in a smallpox vaccination scar
Author(s) -
Ramón M. Pujol,
J. Monmany,
Sílvia Bagué,
Abdulrahman Alomar
Publication year - 2000
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.2000.00595.x
Subject(s) - medicine , infiltration (hvac) , dermatology , erythema , smallpox , graves' disease , vaccination , disease , smallpox vaccine , pathology , biochemistry , chemistry , physics , gene , vaccinia , thermodynamics , recombinant dna
We describe a 54‐year‐old woman with diffuse myxoedematous infiltration at the site of a smallpox vaccination scar as the presenting symptom of Graves' disease. Associated features included acute ocular symptoms (vascular congestion of the sclera, epiphora and blurred vision) and transient erythema on both shins. However, there were no signs of pretibial myxoedema. A number of neoplastic, inflammatory and systemic diseases may localize to scar tissue in skin, including at smallpox vaccination sites, but this case demonstrates the unusual occurrence of myxoedematous infiltration at such a site and illustrates a most atypical cutaneous presentation of Graves'disease.