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Transient leukaemia cutis in chronic lymphocytic leukaemia
Author(s) -
WAKELIN S.H.,
YOUNG E.,
KELLY S.,
TURNER M.
Publication year - 1997
Publication title -
clinical and experimental dermatology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.587
H-Index - 78
eISSN - 1365-2230
pISSN - 0307-6938
DOI - 10.1046/j.1365-2230.1997.1890613.x
Subject(s) - medicine , cutis , pathology , scars , lymphocytic infiltration , dermatology , clearance , urology
Leukaemia cutis arises due to cutaneous infiltration of neoplastic leukocytes or their precursors. Recent evidence suggests that this sign does not necessarily herald a poor prognosis. We describe a 72‐year‐old woman with B‐cell chronic lymphatic leukaemia (CLL) who developed a papular eruption on her breast at the site of a recent herpetic eruption. Histology and immunostaining showed a dense dermal B‐cell infiltrate in keeping with leukaemia cutis. The papules cleared in 6 months without treatment, leaving atrophic scars. The histological features and possible aetiological mechanisms of post‐herpetic papular eruptions in CLL are reviewed.