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What can we learn from late‐onset and occupational asthma?
Author(s) -
Alberto Papi,
Lorenzo Corbetta,
Leonardo Fabbri
Publication year - 1998
Publication title -
clinical and experimental allergy
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.462
H-Index - 154
eISSN - 1365-2222
pISSN - 0954-7894
DOI - 10.1046/j.1365-2222.1998.028s5174.x
Subject(s) - asthma , occupational asthma , medicine , psychology , immunology
Late‐onset asthma and occupational asthma may provide interesting models of human asthma to compare with the most frequent type of atopic early‐onset asthma. The discovery of similarities and discrepancies in the aetiology and pathogenesis of these different diseases might provide new insights on different mechanisms producing the same phenotype and, thus, by recognizing the different underlying mechanisms of the different forms of asthma, may allow better targeting of prevention and treatment. Occupational asthma, in addition to being a late‐onset asthma, provides the unique opportunity to study the development of asthma under measurable exposure conditions, and consequently to examine the effect of cessation of exposure which, at variance with allergen avoidance, is possible in most of the cases.