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Diagnostic value of d ‐dimer in patients with a moderate pretest probability of deep venous thrombosis
Author(s) -
Aguilar Carlos,
Martinez Angela,
Martinez Angel,
Del Rio Concepcion,
Vazquez Mar,
Rodriguez Francisco J.
Publication year - 2002
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1046/j.1365-2141.2002.03614.x
Subject(s) - pre and post test probability , d dimer , medicine , venous thrombosis , thrombosis , predictive value , venous thromboembolism
Summary. The negative predictive value (NPV) of d ‐dimer (DD) for the exclusion of venous thromboembolism is, overall, high and tends to increase as clinical pretest probability decreases. We have assessed the accuracy of a diagnostic protocol including clinical evaluation and DD in 134 outpatients presenting with a moderate pretest probability of proximal deep venous thrombosis (DVT). In these patients, a negative DD value safely excluded DVT (NPV 100%, 95% CI 85–100) In our experience, these results are equivalent to those found for low‐pretest probability patients and therefore the same diagnostic strategy can be used for both risk groups.