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Absence of platelet response after eradication of Helicobacter pylori infection in patients with chronic idiopathic thrombocytopenic purpura
Author(s) -
Jarque I.,
Andreu R.,
Llopis I.,
De la Rubia J.,
Gomis F.,
Senent L.,
Jiménez C.,
Martín G.,
Martínez J. A.,
Sanz G. F.,
Ponce J.,
Sanz M. A.
Publication year - 2001
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1046/j.1365-2141.2001.03194.x
Subject(s) - helicobacter pylori , medicine , thrombocytopenic purpura , gastroenterology , platelet , helicobacter pylori infection , spirillaceae , purpura (gastropod) , immunology , gastritis , ecology , biology
Eradication of Helicobacter pylori infection has been associated with the correction of thrombocytopenia in patients with idiopathic thrombocytopenic purpura (ITP). We have analysed the response to eradication of H. pylori in a series of 56 adult patients with chronic ITP. Forty patients had H. pylori infection (71%) that was eradicated in 23 of 32 evaluable patients (72%). Platelet counts did not significantly vary according to H. pylori treatment outcome . Three of 56 patients (5%) achieved a partial response attributable to H. pylori eradication. Therefore, detection of H. pylori infection should not be routinely included in the initial work‐up of ITP.