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Chronic disseminated intravascular coagulation after surgery for abdominal aortic aneurysm: clinical and haemostatic response to dalteparin
Author(s) -
Cummins David,
Segal Helen,
Hunt Beverley J.,
Awad Reda,
Maddox Anthony
Publication year - 2001
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1046/j.1365-2141.2001.02817.x
Subject(s) - medicine , fibrinolysis , abdominal aortic aneurysm , disseminated intravascular coagulation , surgery , fibrinogen , aneurysm , aortic aneurysm , heparin , coagulation
A 77‐year‐old man developed chronic disseminated intravascular coagulation (DIC) after surgical repair of a large infrarenal aortic aneurysm. Self‐administered subcutaneous dalteparin therapy (5000 units o.d.) led to rapid relief of symptoms and sustained improvements in his platelet count and fibrinogen level; activation of coagulation and fibrinolysis appeared to be relatively unaffected. Long‐term treatment with low‐molecular‐weight heparin can provide good symptomatic control of chronic DIC associated with abdominal aortic aneurysm.