z-logo
Premium
Two‐step immunoablative treatment with autologous peripheral blood CD34 + cell transplantation in an 8‐year‐old boy with autoimmune haemolytic anaemia
Author(s) -
Paillard C.,
Kanold J.,
Halle P.,
Yakouben K.,
Boiret N.,
Rapatel C.,
Berger M.,
Malpuech G.,
Deméocq F.
Publication year - 2000
Publication title -
british journal of haematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.907
H-Index - 186
eISSN - 1365-2141
pISSN - 0007-1048
DOI - 10.1046/j.1365-2141.2000.02281.x
Subject(s) - haemolysis , medicine , transplantation , autoimmune disease , peripheral blood , chemotherapy , complete remission , immunology , surgery , disease
Life‐threatening haemolysis in children with autoimmune haemolytic anaemia (AIHA) occurs rarely. Many cases of severe autoimmune disease are currently treated with immunosuppressive high‐dose chemotherapy and autograft. We report here a case of a child with severe AIHA who did not respond to conventional treatments, but was cured with an autologous peripheral blood CD34 + cell transplantation. After d 16 post autograft, no further red cell transfusions were required. At 20 months post autograft, haematological complete remission persists.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here